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1. Vet Clin North Am Exot Anim Pract. 2023 Jan;26(1):151-174. doi: 10.1016/j.cvex.2022.07.005.
Treatment of Pain in Rats, Mice, and Prairie Dogs.
Oates R(1), Tarbert DK(2).
Author information: (1)Research and Teaching Animal Care Program, University of California – Davis, One Shields Avenue, Davis, CA 95616, USA. Electronic address: firstname.lastname@example.org. (2)Companion Exotic Animal Medicine and Surgery Service, Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California – Davis, One Shields Avenue, Davis, CA 95616, USA.
Recent myomorph and scuiromorph rodent analgesia studies are reviewed and evaluated for potential clinical application. Differences between laboratory animal studies and clinical use in diseased animals are discussed. Analgesia classes reviewed include local anesthetics, nonsteroidal anti-inflammatories, acetaminophen, opioids, and adjuvants such as anticonvulsants. Routes of administration including sustained-release mechanisms are discussed, as are reversal agents. Drug interactions are reviewed in the context of beneficial multimodal analgesia as well as potential adverse effects. Dosage recommendations for clinical patients are explored.
Published by Elsevier Inc.
DOI: 10.1016/j.cvex.2022.07.005 PMID: 36402479 [Indexed for MEDLINE]